Article
Comprehensive evaluation of the association of APOE genetic variation with plasma lipoprotein traits in U.S. whites and African blacks.
PloS one - 1 Jan 2014
Radwan Zaheda H, Wang Xingbin, Waqar Fahad, Pirim Dilek, Niemsiri Vipavee, Hokanson John E, Hamman Richard F, Bunker Clareann H, Barmada M Michael, Demirci F Yesim, Kamboh M Ilyas
Abstract excerpt
Although common APOE genetic variation has a major influence on plasma LDL-cholesterol, its role in affecting HDL-cholesterol and triglycerides is not well established. Recent genome-wide association studies suggest that APOE also affects plasma variation in HDL-cholesterol and triglycerides. It is thus important to resequence the APOE gene to identify both common and uncommon variants that affect plasma lipid...
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