Article

Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted

2024-03-25

Abstract excerpt

Tissue-resident memory CD8 T cells (T RM ) kill infected cells and recruit additional immune cells to limit pathogen invasion at barrier sites. Small intestinal (SI) T RM cells consist of distinct subpopulations with higher expression of effector molecules or greater memory potential. We hypothesized that occupancy of diverse anatomical niches imprints these distinct T RM transcriptional programs. We leveraged...

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Literature Corpus work: f51be46e-e1cb-5847-b7f9-3232bec5c70b
DOI: 10.1101/2024.03.20.585130

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