Article
Axes of heterogeneity in human tissue-resident memory T cells.
Immunological reviews - 1 Jul 2023
Szabo Peter A
Abstract excerpt
Tissue-resident memory T cells (TRM) represent a dedicated layer of localized immune memory in virtually every organ throughout the human body. By virtue of their long-term residence in disparate tissues, TRM are shaped by a myriad of site-specific influences and exhibit remarkable heterogeneity in form and function. Here, we review the major axes by which TRM vary, including their surface phenotypes,...
Topics
- Humans
- Memory T Cells
- Immunologic Memory
- Phenotype
- Cell Differentiation
- CD8-Positive T-Lymphocytes
