Article

Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans

2022-09-19

Abstract excerpt

The development of human adaptive immunity progresses faster than previously appreciated, with the emergence of memory CD4 + T cells alongside regulatory T (Treg) cells by the second trimester of pregnancy. We previously identified a prenatal-specific subset of PLZF + CD4 + T cells with heightened effector potential that accounted for most memory T cells in the developing intestine and accumulated in the cord b...

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Literature Corpus work: 2f895d10-04f5-5ef3-bbab-14e3c8ec0afe
DOI: 10.1101/2022.09.19.508328

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Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humansDOI 10.1101/2022.09.19.508328Read

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