Article

Regional Cell Atlas of Human Intestine Shapes Distinct Immune Surveillance

2021-09-15

Abstract excerpt

Regional intestinal immune surveillance remains obscure. In this study, we integrated single-cell RNA sequencing and spatial transcriptomics to create a regional atlas of fetal and adult intestines, consisting of 59 cell subsets, of which eight new subsets and ILCs transition states were identified. Results revealed that microenvironment determines in-situ cell differentiation and shapes the regional molecular cha...

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Literature Corpus work: 8293cd74-440e-5364-8ec6-183cffe010a3
DOI: 10.1101/2021.09.13.459999

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