Article

IL-1β/IL-6 signaling circuit in the tumor microenvironment drives prostate cancer development

2026-07-31

Abstract excerpt

Despite considerable progress in elucidating mechanisms leading to castration-resistant prostate cancer (CRPC), insight into the early stages of prostate cancer initiation and progression remains limited. Genomic drivers of prostate cancer initiation have been defined through patient tumor sequencing, but the subsequent events responsible for local tissue invasion are poorly understood. Here we leverage a well-stu...

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Literature Corpus work: f4eab858-21c6-5f33-bbbf-ea2532b31f31
DOI: 10.64898/2026.07.30.741572

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