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Distinct mesenchymal cell states mediate prostate cancer progression

2023-04-01

Abstract excerpt

<h4>Summary</h4> Alterations in tumor stroma influence prostate cancer progression and metastatic potential. However, the molecular underpinnings of this stromal-epithelial crosstalk are largely unknown. Here, we compare mesenchymal cells from four genetically engineered mouse models (GEMMs) of prostate cancer representing different stages of the disease to their wild-type (WT) counterparts by single-cell RNA seq...

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Literature Corpus work
a91e2649-ad77-5afd-a347-111febfdec69
DOI
10.1101/2023.03.29.534769
Open publication

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Distinct mesenchymal cell states mediate prostate cancer progressionDOI 10.1101/2023.03.29.534769
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