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Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer

28 Aug 2024

Abstract excerpt

How prostate cancer cells and their precursors mediate changes in the tumor microenvironment (TME) to drive prostate cancer progression is unclear, in part due to the inability to longitudinally study the disease evolution in human tissues. To overcome this limitation, we perform extensive single-cell RNA-sequencing (scRNA-seq) and molecular pathology of the comparative biology between human prostate cancer and...

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Cancer Immunotherapy and Biomarkers
Immunotherapy and Immune Responses
Prostate Cancer Treatment and Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39198404
DOI: 10.1038/s41467-024-51450-2

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