Article

Joint eQTL mapping and Inference of Gene Regulatory Network Improves Power of Detecting both <i>cis</i> - and <i>trans</i> -eQTLs

2020-04-25

Abstract excerpt

<h4>Motivation</h4> Genetic variations of expression quantitative trait loci (eQTLs) play a critical role in influencing complex traits and diseases development. Two main factors that affect the statistical power of detecting eQTLs are: 1) relatively small size of samples available, and 2) heavy burden of multiple testing due to a very large number of variants to be tested. The later issue is particularly severe...

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Literature Corpus work: f477aaed-6912-5d7b-b4a9-70b0eb87d787
DOI: 10.1101/2020.04.23.058735

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