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Article

Joint variable selection and network modeling for detecting eQTLs.

Statistical applications in genetics and molecular biology - 20 Feb 2020

Cao Xuan, Ding Lili, Mersha Tesfaye B

Abstract excerpt

In this study, we conduct a comparison of three most recent statistical methods for joint variable selection and covariance estimation with application of detecting expression quantitative trait loci (eQTL) and gene network estimation, and introduce a new hierarchical Bayesian method to be included in the comparison. Unlike the traditional univariate regression approach in eQTL, all four methods correlate...

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PMID: 32078577
DOI: 10.1515/sagmb-2019-0032

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