Article
Sparse regression models for unraveling group and individual associations in eQTL mapping.
BMC bioinformatics - 22 Mar 2016
Cheng Wei, Shi Yu, Zhang Xiang, Wang Wei
Abstract excerpt
BACKGROUND: As a promising tool for dissecting the genetic basis of common diseases, expression quantitative trait loci (eQTL) study has attracted increasing research interest. Traditional eQTL methods focus on testing the associations between individual single-nucleotide polymorphisms (SNPs) and gene expression traits. A major drawback of this approach is that it cannot model the joint effect of a set of SNPs on...
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