Article

Predicting drug combination response surfaces

2024-04-05

Abstract excerpt

Prediction of drug combination responses is a research question of growing importance for cancer and other complex diseases. Current machine learning approaches generally consider predicting either drug combination synergy summaries or single combination dose-response values, which fail to appropriately model the continuous nature of the underlying dose-response combination surface and can lead to inconsistencies...

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Literature Corpus work: f3f3f88d-c11e-541a-9b87-088e52ed5737
DOI: 10.1101/2024.04.03.586729

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