Article

Multi-output prediction of dose-response curves enable drug repositioning and biomarker discovery

2023-12-18

Abstract excerpt

<title>Abstract</title> <p>Drug screening plays a crucial role in the development of innovative therapeutics for various diseases. In this study, we propose a novel approach using probabilistic multi-output models to predict drug response at all doses and uncover their biomarkers. By leveraging genomic features and chemical properties of drugs, our multi-output Gaussian Process (MOGP) models provide a comprehensi...

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Identifiers and source

Literature Corpus work: 5799832d-9757-55b6-99c9-487110d82c0c
DOI: 10.21203/rs.3.rs-3448859/v1

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