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Explainable machine learning prediction of synergistic drug combinations for precision cancer medicine

2018-05-27

Abstract excerpt

Although combination therapy has been a mainstay of cancer treatment for decades, it remains challenging, both to identify novel effective combinations of drugs and to determine the optimal combination for a particular patient’s tumor. While there have been several recent efforts to test drug combinations in vitro , examining the immense space of possible combinations is far from being feasible. Thus, it is cruci...

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Literature Corpus work
a3eef1d7-8b9a-587b-9d87-e8dc1f5a70f0
DOI
10.1101/331769
Open publication

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Explainable machine learning prediction of synergistic drug combinations for precision cancer medicineDOI 10.1101/331769
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