Article

Dynamic hinge-motion of PfRIPR revealed by malaria invasion inhibitory antibodies

2026-01-14

Abstract excerpt

<h4>Summary</h4> The PfPCRCR complex is essential for invasion of human erythrocytes by the deadliest malaria parasite, Plasmodium falciparum . Antibodies against each subunit of PfPCRCR prevent erythrocyte invasion and the PfRH5 component is currently the most advanced blood-stage malaria vaccine. Central within PfPCRCR is PfRIPR. This complex molecule contains a core and a flexible tail and allows PfPCRCR to b...

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Literature Corpus work: f3e6c97b-f47b-5582-8c75-e0298cc1a8a6
DOI: 10.64898/2026.01.14.699498

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