Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for <i>Plasmodium falciparum</i> erythrocyte invasion

Abstract excerpt

Erythrocyte invasion by Plasmodium falciparum merozoites is a highly intricate process in which Plasmodium falciparum reticulocyte binding-like homologous protein 5 (PfRH5) is an indispensable parasite ligand that binds with its erythrocyte receptor, Basigin. PfRH5 is a leading blood-stage vaccine candidate because it exhibits limited polymorphisms and elicits potent strain-transcending parasite neutralizing...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Malaria Research and Control
• Share to Signaling Pathways in Disease
• Share to Venomous Animal Envenomation and Studies