Article

Genetic Diversity of the Malaria Vaccine Candidate PfRIPR in a High Transmission Region of Senegal

2025-09-29

Abstract excerpt

<h4>Summary</h4> RH5-Interacting Protein (RIPR) is essential for the invasion of Plasmodium into host red blood cells and is currently being studied as a novel malaria vaccine candidate in Phase 1a clinical trials. To study the genetic diversity of RIPR, deep amplicon sequencing was used to identify RIPR mutations in Plasmodium falciparum clinical isolates (n=89) collected in Kédougou, a high malaria transmission...

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Literature Corpus work: a401bea8-c42b-54db-a3e7-c6ca998709bc
DOI: 10.1101/2025.09.23.25335263

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