Article

Evaluating the potential of cross-species neutralization of anti-PfCyRPA and anti-PfRIPR Monoclonal Antibodies

2025-11-04

Abstract excerpt

<h4>ABSTRACT</h4> PfCyRPA and PfRIPR are promising next-generation malaria blood-stage vaccine candidate antigens that play an essential role in erythrocyte invasion of Plasmodium falciparum . CyRPA and RIPR orthologs are present in all human-infecting Plasmodium species, suggesting the potential for a cross-species vaccine. Using Growth Inhibition Assays (GIA), this study investigates seven anti-PfCyRPA and th...

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Literature Corpus work: 286713a2-6aca-5555-bafd-1f5e2922c8e8
DOI: 10.1101/2025.11.03.682341

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