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Evidence against altered excitatory/inhibitory balance in the posteromedial cortex of young adult APOE E4 carriers: a resting state <sup>1</sup> H-MRS study

2021-05-14

Abstract excerpt

A strategy to gain insight into early changes that may predispose people to Alzheimer’s disease is to study the brains of younger cognitively healthy people that are at increased genetic risk of AD. The Apolipoprotein (APOE) E4 allele is the strongest genetic risk factor for AD, and several neuroimaging studies comparing APOE E4 carriers with non-carriers at age ~20-30 have detected hyperactivity (or reduced deact...

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Literature Corpus work
f3d71915-74aa-5f1a-9189-574416a36bdb
DOI
10.1101/2021.05.12.443879
Open publication

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Evidence against altered excitatory/inhibitory balance in the posteromedial cortex of young adult APOE E4 carriers: a resting state <sup>1</sup> H-MRS studyDOI 10.1101/2021.05.12.443879
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