Article

Combining Aperiodic 1/f Slopes and Brain Simulation: An EEG/MEG Proxy Marker of Excitation/Inhibition Imbalance in Alzheimer’s Disease

2022-12-22

Abstract excerpt

Accumulation and interaction of amyloid-beta (Aβ) and tau proteins during progression of Alzheimer’s disease (AD) are shown to tilt neuronal circuits away from balanced excitation/inhibition (E/I). Current available techniques for noninvasive interrogation of E/I in the intact human brain, e.g., magnetic resonance spectroscopy (MRS), are highly restrictive (i.e., limited spatial extent), have low temporal and spat...

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Literature Corpus work: e3479283-a94e-5843-a82e-bfa5d94f4cdd
DOI: 10.1101/2022.12.21.521529

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