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Differential effects of aging, Alzheimer’s pathology, and <i>APOE4</i> on longitudinal functional connectivity and episodic memory in older adults

2024-12-17

Abstract excerpt

<h4>INTRODUCTION</h4> Both aging and Alzheimer’s disease (AD) affect episodic memory networks. How this relates to region-specific early differences in functional connectivity (FC), however, remains unclear. <h4>METHODS</h4> We assessed resting-state FC strength in the medial temporal lobe (MTL) - posteromedial cortex (PMC) - prefrontal network and cognition over two years in cognitively normal older adults from...

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Literature Corpus work
c052598d-8c1c-5d64-bb89-30039b7a1852
DOI
10.1101/2024.12.11.627967
Open publication

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Differential effects of aging, Alzheimer’s pathology, and <i>APOE4</i> on longitudinal functional connectivity and episodic memory in older adultsDOI 10.1101/2024.12.11.627967
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