Article

Disrupted excitation-inhibition balance in cognitively normal individuals at risk of Alzheimer’s disease

2023-08-22

Abstract excerpt

<h4>Background</h4> Sex differences impact Alzheimer’s disease (AD) neuropathology, but cell-to-network level dysfunctions in the prodromal phase are unclear. Alterations in hippocampal excitation-inhibition balance (EIB) have recently been linked to early AD pathology. <h4>Objective</h4> Examine how AD risk factors (age, APOE-ɛ4, amyloid-β) relate to hippocampal EIB in cognitively normal males and females using...

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Literature Corpus work: 3d9aacb9-9592-517d-a5fd-0f2120e43e46
DOI: 10.1101/2023.08.21.554061

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