Article

A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

2018-08-03

Abstract excerpt

Schizophrenia is a complex highly heritable disorder. Genome-wide association studies have identified multiple loci that influence the risk of developing schizophrenia, although the causal variants driving these associations and their impacts on specific genes are largely unknown. Here we link genetic findings to gene expression in the human brain by performing a transcriptome-wide association study (TWAS) in whic...

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Literature Corpus work: f2309b59-e865-580e-81a9-40c9ac616696
DOI: 10.1101/384560

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