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Article

The integrated landscape of causal genes and pathways in schizophrenia.

Translational psychiatry - 15 Mar 2018

Ma Changguo, Gu Chunjie, Huo Yongxia, Li Xiaoyan, Luo Xiong-Jian

Abstract excerpt

Genome-wide association studies (GWAS) have identified more than 100 loci that show robust association with schizophrenia risk. However, due to the complexity of linkage disequilibrium and gene regulatory, it is challenging to pinpoint the causal genes at the risk loci and translate the genetic findings from GWAS into disease mechanism and clinical treatment. Here we systematically predicted the plausible...

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Identifiers

PMID: 29540662
DOI: 10.1038/s41398-018-0114-x
PMCID: PMC5851982

Genes

CNTN4
MMP16
PSMA4
TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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