Article
Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 2014
Dixson Luanna, Walter Henrik, Schneider Michael, Erk Susanne, Schäfer Axel, Haddad Leila, Grimm Oliver, Mattheisen Manuel, Nöthen Markus M, Cichon Sven, Witt Stephanie H, Rietschel Marcella, Mohnke Sebastian, Seiferth Nina, Heinz Andreas, Tost Heike, Meyer-Lindenberg Andreas
Abstract excerpt
Functional interactions between the dorsolateral prefrontal cortex and hippocampus during working memory have been studied extensively as an intermediate phenotype for schizophrenia. Coupling abnormalities have been found in patients, their unaffected siblings, and carriers of common genetic variants associated with schizophrenia, but the global genetic architecture of this imaging phenotype is unclear. To...
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