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Article

A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia.

Human molecular genetics - 1 Jan 2020

Hall Lynsey S, Medway Christopher W, Pain Oliver, Pardiñas Antonio F, Rees Elliott G, Escott-Price Valentina, Pocklington Andrew, Bray Nicholas J, Holmans Peter A, Walters James T R, Owen Michael J, O'Donovan Michael C

Abstract excerpt

Schizophrenia is a complex highly heritable disorder. Genome-wide association studies (GWAS) have identified multiple loci that influence the risk of developing schizophrenia, although the causal variants driving these associations and their impacts on specific genes are largely unknown. We identify a significant correlation between schizophrenia risk and expression at 89 genes in the dorsolateral prefrontal...

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Identifiers

PMID: 31691811
DOI: 10.1093/hmg/ddz253
PMCID: PMC7416679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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