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Article

Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity.

Biological psychiatry - 1 Jan 2015

Hall Jeremy, Trent Simon, Thomas Kerrie L, O'Donovan Michael C, Owen Michael J

Abstract excerpt

Recent large-scale genomic studies have revealed two broad classes of risk alleles for schizophrenia: a polygenic component of risk mediated through multiple common risk variants and rarer more highly penetrant submicroscopic chromosomal deletions and duplications, known as copy number variants. The focus of this review is on the emerging findings from the latter and subsequent exome sequencing data of smaller,...

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Identifiers

PMID: 25152434
DOI: 10.1016/j.biopsych.2014.07.011

Genes

PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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