Article

Preserved suppressive function despite loss of Foxp3: insights into the identity of regulatory T cells

2025-01-22

Abstract excerpt

Regulatory T (Treg) cells are essential for maintaining immune homeostasis, with Foxp3 acting as the master transcription factor governing their differentiation and function. The acquisition of effector signatures in Treg cells is closely tied to the surrounding tissue-specific immune environment and typically occurs alongside Foxp3 expression. In this study, we investigated the transcriptomic and functional conse...

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Literature Corpus work: f1bbff37-71c6-5da2-b035-af7063ceb73e
DOI: 10.1101/2025.01.17.633544

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