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Article

Natural and Induced T Regulatory Cells in Cancer

1 Jan 2013

Abstract excerpt

CD4+Foxp3+ T regulatory (Treg) cells control many facets of immune responses ranging from autoimmune diseases, to inflammatory conditions, and cancer in an attempt to maintain immune homeostasis. Natural Treg (nTreg) cells develop in the thymus and constitute a critical arm of active mechanisms of peripheral tolerance particularly to self antigens. A growing body of knowledge now supports the existence of induced...

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PMID: 23874336
DOI: 10.3389/fimmu.2013.00190

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