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Article

Inflammation-associated genes: risks and benefits to Foxp3+ regulatory T-cell function.

Immunology - 1 Oct 2015

O'Connor Richard A, Anderton Stephen M

Abstract excerpt

Foxp3(+) regulatory T (Treg) cells prevent the development of autoimmunity and immunopathology, as well as maintaining homeostasis and tolerance to commensal microorganisms. The suppressive activity of Treg cells is their defining characteristic, generating great interest in their therapeutic potential. However, suppressive and effector functions are not entirely exclusive. Considerable evidence points to the...

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Identifiers

PMID: 26190495
DOI: 10.1111/imm.12507
PMCID: PMC4582961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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