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Article

Regulatory T cells and their roles in immune dysregulation and allergy.

Immunologic research - 1 May 2014

Pellerin Laurence, Jenks Jennifer A, Bégin Philippe, Bacchetta Rosa, Nadeau Kari C

Abstract excerpt

The main function of the immune system is to fight off potential infections, but also to maintain its activity below a level that would trigger self-reactivity. Regulatory T cells (Tregs) such as forkhead box P3(+) (FOXP3) Tregs and type 1 regulatory T cells (Tr1) play an essential role in this active process, using several distinct suppressive mechanisms. A wide range of pathologies have been associated with...

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Topics

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Share to FOXP3 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24781194
DOI: 10.1007/s12026-014-8512-5
PMCID: PMC4161462

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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