Article

Edge effects in game theoretic dynamics of spatially structured tumours

2015-01-23

Abstract excerpt

<h4>Background</h4> Analysing tumour architecture for metastatic potential usually focuses on phenotypic differences due to cellular morphology or specific genetic mutations, but often ignore the cell’s position within the heterogeneous substructure. Similar disregard for local neighborhood structure is common in mathematical models. <h4>Methods</h4> We view the dynamics of disease progression as an evolutionary...

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Literature Corpus work: f11f066c-ecdc-5328-8061-b896ef6f7d26
DOI: 10.1101/014233

Open publication

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