Article
Cancer heterogeneity and multilayer spatial evolutionary games.
Biology direct - 13 Oct 2016
Świerniak Andrzej, Krześlak Michał
Abstract excerpt
BACKGROUND: Evolutionary game theory (EGT) has been widely used to simulate tumour processes. In almost all studies on EGT models analysis is limited to two or three phenotypes. Our model contains four main phenotypes. Moreover, in a standard approach only heterogeneity of populations is studied, while cancer cells remain homogeneous. A multilayer approach proposed in this paper enables to study heterogeneity of...
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