Article

Accurate genome-wide germline profiling from decade-old archival tissue DNA reveals the contribution of common variants to precancer disease outcome

2022-04-05

Abstract excerpt

<h4>Background</h4> Inherited variants have been shown to contribute to cancer risk, disease progression, and response to treatment. Such studies are, however, arduous to conduct, requiring large sample sizes, cohorts or families, and more importantly, a long follow-up to measure a relevant outcome such as disease onset or progression. Unless collected for a dedicated study, germline DNA from blood or saliva are t...

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Literature Corpus work: f10b2997-d918-58ca-a340-838c1b223bae
DOI: 10.1101/2022.03.31.22273116

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