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Applying whole-genome and whole-exome sequencing in breast cancer: a review of the landscape.

Breast cancer (Tokyo, Japan) - 1 Nov 2024

Ganatra Hetvi, Tan Joecelyn Kirani, Simmons Ana, Bigogno Carola Maria, Khurana Vatsala, Ghose Aruni, Ghosh Adheesh, Mahajan Ishika, Boussios Stergios, Maniam Akash, Ayodele Olubukola

Abstract excerpt

Whole-genome sequencing (WGS) and whole-exome sequencing (WES) are crucial within the context of breast cancer (BC) research. They play a role in the detection of predisposed genes, risk stratification, and identification of rare single nucleotide polymorphisms (SNPs). These technologies aid in the discovery of associations between various syndromes and BC, understanding the tumour microenvironment (TME), and...

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Breast Neoplasms
Cancer Genomics and Diagnostics
Exome Sequencing
Genetic Predisposition to Disease
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Tumor Microenvironment

Whole Genome Sequencing

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Identifiers

PMID: 39190283
DOI: 10.1007/s12282-024-01628-9
PMCID: PMC11489287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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