Article

Monocyte-specific changes in gene expression implicate <i>LACTB2</i> and <i>PLIN2</i> in Alzheimer’s disease

2020-06-06

Abstract excerpt

More than 50 genetic loci have been identified as being associated with Alzheimer’s disease (AD) from genome-wide association studies (GWAS) and many of these are involved in immune pathways and lipid metabolism. Therefore, we performed a transcriptome-wide association study (TWAS) of immune-relevant cells, to study the mis-regulation of genes implicated in AD. We used expression and genetic data from naive and in...

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Literature Corpus work: f0dd4deb-acb1-5de4-851f-0bfbbf277922
DOI: 10.1101/2020.06.05.136275

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Monocyte-specific changes in gene expression implicate <i>LACTB2</i> and <i>PLIN2</i> in Alzheimer’s diseaseDOI 10.1101/2020.06.05.136275Read

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