Article

Dynamic hybrid-hydrogel lung models decouple matrix composition, stiffness, and fibroblast memory to define distinct drivers of fibrotic progression

2026-07-22

Abstract excerpt

Idiopathic pulmonary fibrosis is a devastating chronic lung disease characterized by progressive scarring of the lung, which leads to impaired gas exchange and ultimately death. While research has provided us with extensive understanding on end-stage disease, the factors that lead to forward-feedback loops of fibrotic progression are still not fully known. Cell intrinsic activation, pathological extracellular matr...

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Literature Corpus work: f0540cd5-cac7-57f0-8337-24091eeea595
DOI: 10.64898/2026.07.21.739843

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