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Lung Extracellular Matrix and Fibroblast Function

1 Mar 2015

Abstract excerpt

Extracellular matrix (ECM) is a tissue-specific macromolecular structure that provides physical support to tissues and is essential for normal organ function. In the lung, ECM plays an active role in shaping cell behavior both in health and disease by virtue of the contextual clues it imparts to cells. Qualities including dimensionality, molecular composition, and intrinsic stiffness all promote normal function...

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PMID: 25830832
DOI: 10.1513/annalsats.201406-240mg

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