Article

Transitional alveolar epithelial cells and microenvironmental stiffness synergistically drive fibroblast activation in three-dimensional hydrogel lung models

2022-05-25

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease that progressively and irreversibly alters the lung parenchyma, eventually leading to respiratory failure. The study of this disease has been historically challenging due to the myriad of complex processes that contribute to fibrogenesis and the inherent difficulty in accurately recreating the human pulmonary environment in vitro . Here, we describ...

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Literature Corpus work: d12ea024-d4e4-5d3e-8209-474f19a0b29b
DOI: 10.1101/2022.05.24.493246

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