Article

Efficient estimation for large-scale linkage disequilibrium patterns of the human genome

2023-06-20

Abstract excerpt

In this study, we proposed an efficient algorithm (X-LD) for estimating LD patterns for a genomic grid, which can be of inter-chromosomal scale or of small segments. Compared with conventional methods, the proposed method was significantly faster, dropped from 𝒪 ( nm 2 ) to 𝒪 ( n 2 m )— n the sample size and m the number of SNPs, and consequently we were permitted to explore in depth unknown or reveal long-a...

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Literature Corpus work: f0505c8f-682b-53da-bb09-766d1ab53e07
DOI: 10.1101/2023.06.18.545475

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