Article
A fine-scale genetic map of the Japanese population.
Clinical genetics - 1 Sept 2024
Takayama Jun, Makino Satoshi, Funayama Takamitsu, Ueki Masao, Narita Akira, Murakami Keiko, Orui Masatsugu, Ishikuro Mami, Obara Taku, Kuriyama Shinichi, Yamamoto Masayuki, Tamiya Gen
Abstract excerpt
Genetic maps are fundamental resources for linkage and association studies. A fine-scale genetic map can be constructed by inferring historical recombination events from the genome-wide structure of linkage disequilibrium-a non-random association of alleles among loci-by using population-scale sequencing data. We constructed a fine-scale genetic map and identified recombination hotspots from 10 092 551 bi-allelic...
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