Article
[Linkage disequilibrium in the human genome and its exploitation].
Archives de l'Institut Pasteur de Tunis - 1 Jan 2005
Kharrat N, Rebaï M, Rebaï A
Abstract excerpt
This present review gives an overview on Linkage disequilibrium (LD), its measures and its different utilizations in human genetics studies. In the first part, we provide a detailed and a simplified presentation focusing on the definition of LD, its measures and the major software for its evaluation. Thereafter, we describe and discuss the biological and evolutionary mechanisms which create, remodel, maintain or...
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