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Article

GWLD: an R package for genome-wide linkage disequilibrium analysis.

G3 (Bethesda, Md.) - 30 Aug 2023

Zhang Rong, Wu Huaxuan, Li Yasai, Huang Zehang, Yin Zongjun, Yang Cai-Xia, Du Zhi-Qiang

Abstract excerpt

Linkage disequilibrium (LD) analysis is fundamental to the investigation of the genetic architecture of complex traits (e.g. human disease, animal and plant breeding) and population structure and evolution dynamics. However, until now, studies primarily focus on LD status between genetic variants located on the same chromosome. Moreover, genome (re)sequencing produces unprecedented numbers of genetic variants,...

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PMID: 37431944
DOI: 10.1093/g3journal/jkad154
PMCID: PMC10468308

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