Allele frequency patterns of 78,122,254 SNPs illuminate diverse possible evolutionary trajectories of human populations.

Abstract excerpt

The history of human population migration and mixing is manifested in the allele frequency variations of all SNPs in the genomes. We proposed an algorithm to infer the population allele frequency patterns of individual loci and identified 71 unique patterns from the 78,122,254 loci of the 1000 Genomes (1000G) data. In nearly 90% of the loci, the major alleles dominate the subjects from all populations. Yet the...

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