Article
Linkage disequilibrium and association mapping: an introduction.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Collins Andrew R
Abstract excerpt
The basis for recent developments on the characterization of the linkage-disequilibrium structure of the genome and the application of association mapping to genes for common human diseases is described. Patterns of linkage disequilibrium are now understood, for a number of human populations, in unprecedented detail. This information not only provides a vital resource for the design and execution of powerful...
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