Article

No evidence of association between PGK1 variants and Parkinsons disease

2026-08-21

Abstract excerpt

<h4>Background: </h4> An X-linked levodopa-responsive parkinsonism-epilepsy syndrome has been associated with PGK1, and the gene lies within the previously suspected PD locus PARK12. Objective To examine the association of common and rare PGK1 variants with PD. Methods We analyzed common and rare variants from Accelerated Medicines Partnership - Parkinsons Disease (AMP-PD) and UK Biobank (UKBB, total N=4,523 PD ca...

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Literature Corpus work: eb51c791-73d3-5d26-94c3-ff9cc6d7b21a
DOI: 10.64898/2026.08.18.26360396

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