Article

Deep5hmC: Predicting genome-wide 5-Hydroxymethylcytosine landscape via a multimodal deep learning model

2024-03-06

Abstract excerpt

5-hydroxymethylcytosine (5hmC), a critical epigenetic mark with a significant role in regulating tissue-specific gene expression, is essential for understanding the dynamic functions of the human genome. Using tissue-specific 5hmC sequencing data, we introduce Deep5hmC, a multimodal deep learning framework that integrates both the DNA sequence and the histone modification information to predict genome-wide 5hmC mo...

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Literature Corpus work: 829ef1ae-2e4c-5442-ab39-f9884d0bad4c
DOI: 10.1101/2024.03.04.583444

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