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Cross-disorder genomic structural equation modeling reveals common genetic basis of neuroimmune diseases

2025-08-22

Abstract excerpt

<title>Abstract</title> <p>The genetic architecture underlying neuroimmune syndrome-related traits remains poorly characterized. We employed genomic structural equation modeling (genomic SEM) alongside comprehensive post-GWAS analytical frameworks to identify causal single nucleotide polymorphisms (SNPs) associated with phenotypic variance independent of measured traits, revealing 33 genome-wide significant loci....

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Literature Corpus work
efcb8e24-f8a2-5f7e-900a-5d45d001dc22
DOI
10.21203/rs.3.rs-7328766/v1
Open publication

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Cross-disorder genomic structural equation modeling reveals common genetic basis of neuroimmune diseasesDOI 10.21203/rs.3.rs-7328766/v1
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