Back to search

Article

Genomic Structural Equation Modeling Reveals Latent Phenotypes in the Human Cortex with Distinct Genetic Architecture

2022-11-08

Abstract excerpt

<h4>ABSTRACT</h4> Genetic contributions to human cortical structure manifest pervasive pleiotropy. This pleiotropy may be harnessed to identify unique genetically-informed parcellations of the cortex that are neurobiologically distinct from anatomical, functional, cytoarchitectural, or other cortical parcellation schemes. We investigated genetic pleiotropy by applying genomic structural equation modeling (SEM) to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c5508d5e-4960-5b2f-a306-87c32945b661
DOI
10.1101/2022.11.04.515213
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genomic Structural Equation Modeling Reveals Latent Phenotypes in the Human Cortex with Distinct Genetic ArchitectureDOI 10.1101/2022.11.04.515213
Select a neighboring publication to make it the new centre.