Article

iPSC-Astrocyte morphology reflects patient clinical markers

2023-07-18

Abstract excerpt

Human iPSCs provide powerful cellular models of Alzheimer’s disease (AD) and offer many advantages over non-human models, including the potential to reflect variation in individual-specific pathophysiology and clinical symptoms Previous studies have demonstrated that iPSC-neurons from individuals with Alzheimer’s disease (AD) reflect clinical markers, including β-amyloid (Aβ) levels and synaptic vulnerability. How...

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Literature Corpus work: efcb1695-1a1b-50b4-9735-7e725ec525ed
DOI: 10.1101/2023.07.15.548687

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